The Hidden Hormone Disruptor in Dental Materials: Bis-GMA

When we think about dental fillings or sealants, we usually focus on how long they’ll last or how natural they’ll look. But at a deeper level, what we place in our mouths can have a lasting impact on our entire body — especially when those materials interact with our hormonal system.

One commonly used compound in conventional dentistry is composite resins that contains Bis-GMA, short for bisphenol A-glycidyl methacrylate. While tooth-colored composites are praised for its natural look, it comes with a serious concern that’s not often discussed in the dental chair: it may act as an endocrine disruptor. Now, let’s talk about Bis-GMA and its side affect on the body.

⚠️ What Is Bis-GMA and Why Is It Concerning?

Bis-GMA is a synthetic resin used in many dental composites, adhesives, and sealants. It was originally derived from bisphenol A (BPA) — a chemical widely known for disrupting the body’s endocrine (hormonal) system.

Although manufacturers claim Bis-GMA is more stable and less prone to breaking down into BPA, studies have shown that under certain conditions, such as when restorations are freshly placed, exposed to heat, or acidic environments, this BPA-like compounds can still leach out — even in small amounts.

This is especially concerning because BPA and similar compounds mimic hormones in the body, leading to:

• Hormonal imbalances
• Reproductive concerns
• Thyroid dysfunction
• Increased risk for hormone-sensitive conditions

Even trace exposures can be problematic, especially for individuals with autoimmune conditions, fertility challenges, or heightened chemical sensitivities.

🧬 How Biological Dentists Approach This Differently

A biological dentist is trained to see the bigger picture — recognizing that what goes in your mouth doesn’t stay in your mouth. We know that oral materials can influence immune, neurological, and endocrine health, which is why we avoid materials that contain Bis-GMA, BPA, or any hormone-disrupting compounds.

Instead, our biological dentists in Seattle Dental Care:

• READ material safety sheet to ensure dental materials we use are simple, safe, and without harsh chemicals
• Use BPA-free and Bis-GMA-free alternatives
• Offer ceramic or zirconia-based restorations that are biologically inert
• Recommend biocompatibility testing when needed, to ensure your body will tolerate the materials being used
• Educate patients on the systemic effects of commonly used dental materials

This patient-first, whole-body approach is what sets us apart.

💡 What To Do

If you’re concerned about BPA or Bis-GMA exposure in your dental work, here are a few steps you can take:

• Ask questions before a procedure: What materials will be used? Are they BPA/Bis-GMA-free?
• Choose a biological dentist who prioritizes nontoxic, biocompatible care
• Request ceramic alternatives when appropriate, especially for larger restorations or crowns
• Get informed about what’s already in your mouth

🌿 Your Mouth Is Connected to Your Whole Body

In biological dentistry, we believe your mouth should be a source of health — not hidden toxicity. That’s why we stay educated on the latest research, screen all materials for biocompatibility, and actively avoid known endocrine disruptors like Bis-GMA.

Your body deserves the safest, cleanest materials available - and when it comes to your hormones, even the smallest exposure matters.